Zhenjie Yi joined our lab as an MD student. He is from Xiangya Medical School at Central South University. His interest lies in exploring cellular stress response pathways that may hold promise for benefiting patients undergoing brain surgery. Welcome, Zhenjie!
Anuj Peri joined our lab as an undergraduate researcher. Anuj is currently a freshman at the University of Pittsburgh’s Frederick Honors College majoring in molecular biology. He is interested in molecular genetics and cell biology and their wider impacts on human health, specifically with tackling aging. His goal is to actively participate in research on lysosomal quality control and to acquire insights into treating lysosomal-related diseases throughout his undergraduate career. Welcome, Anuj!
Rae Yang joined our lab as an undergraduate researcher. Rae is currently a first-year college student at the University of Pittsburgh, majoring in Biological Sciences and minoring in Music on the pre-medical track. Rae is intrigued by the correlation between organelle stress and human illnesses, alongside her focus on lysosomal quality control in aging. She's keen to delve deeper into understanding how lysosome dysfunction affects cellular balance and exploring strategies for prompt lysosomal repair that could lead to innovative treatments for neurodegenerative disorders. Welcome, Rae!
Jenny Cheng joined our lab as an undergraduate researcher. Jenny is currently a junior at the University of Pittsburgh majoring in Molecular Biology and minoring in Chemistry and Chinese. Jenny is interested in how organelle stress and damage could be a risk factor in aging and also diseases, and would like to devote into the investigation in extending lifespan by stimulating cellular stress response pathways. With these research experience, Jenny aims to develop an exciting research career. Welcome, Jenny!
The whole lab attended the Aging Research Day at the University Club.
Congratulations to Jeff and Bo who received a poster award for the "STING channel" work!
Ruhi Chand joined our lab as an undergraduate researcher. Ruhi is currently a first-year honors student at the University of Pittsburgh majoring in Neuroscience. She is interested in aging principles and neurodegeneration. Welcome, Ruhi!
The whole lab attended the annual Cell Biology retreat at Pittsburgh Zoo and Aquarium. Congratulations to Haoxiang and Jeff for their poster presentations!
The Tan lab received a MIRA R35 award from NIGMS. Great news for the lab!
Awishi Mondal joined us as a PhD student. Awishi had her B.S. in Zoology and M.S. in Biophysics and Molecular Biology. She is interested in protein-protein interactions, cellular quality control, and drug discovery. Welcome Awishi!
The Tan lab attended Local Traffic 2023 - the 22nd annual Pittsburgh Symposium on Membrane Traffic.
Haoxiang presented his work at the Aging Institute Research in Progress Seminar. Well done, Haoxiang!
Dr. Bo Lyu joined our lab as a senior postdoctoral researcher. Dr. Lyu holds a Ph.D. in genetics and has extensive research experience in molecular and cell biology. Welcome, Dr. Lyu!
Our first review article is accepted by Trends in Cell Biology. Cheers!
The Tan lab joined VMI/Aging Institute holiday party at Sienna Mercato. Cheers!
Jinrui (Jeffrey) Xun joined our lab as a visiting scholar. He is an MD candidate from Xiangya Medical School. He is interested in cellular stress responses that could be potentially targeted for patients' health. Welcome, Jeffrey!
Our recent work on lysosomal repair is published online today at Nature.
In this study, we identified the PITT (phosphoinositide-initiated membrane tethering and lipid transport) pathway as an essential mechanism for rapid lysosomal repair. Congratulations!
A quick fix for lysosomes. Nat Struct Mol Biol 29, 955 (2022).
Phosphoinositide signal for lysosomal membrane repair. Nat Rev Mol Cell Biol 23, 697 (2022).
PITTching in for lysosome repair. Dev Cell. 2022
The PITT pathway: Keeping lysosomes young. Clin Transl Med 12(10): e1097 (2022).
Genetic Engineering & Biotechnology News:
BioArt： Nature | 溶酶体损伤修复的核心机制
Jay was invited to present at ASBMB Lipid Research Division Seminar Series. Looking forward to the seminar at noon on Aug 31, 2022.
Haoxiang Yang joined our lab as a research assistant. Haoxiang has a strong background in computer science. He is learning aging biology and pursuing a future career applying his CS expertise to aging research. Welcome, Haoxiang!
Our new lab is up and running!
Jay was invited for a talk at the 2022 FASEB phospholipid meeting in Jupiter, FL. Congratulations!
The Tan lab is official today in Aging Institute and Department of Cell Biology at University of Pittsburgh!