Jay Tan Lab
Jay Tan Lab
  • Home
  • Research
  • Publications
  • Team
  • Meet the PI
  • News
  • Resources
  • Join
  • More
    • Home
    • Research
    • Publications
    • Team
    • Meet the PI
    • News
    • Resources
    • Join
  • Home
  • Research
  • Publications
  • Team
  • Meet the PI
  • News
  • Resources
  • Join

Jay Xiaojun Tan, PhD

Assistant Professor

Aging Institute

Department of Cell Biology

University of Pittsburgh School of Medicine/UPMC

564 Bridgeside Point I Building

100 Technology Drive

Pittsburgh, PA 15219

Email: Jay.Tan at Pitt.edu


 ACADEMIC TRAINING 

2019 - 2022

  Research Assistant Professor, Aging Institute & Department of Cell   Biology

 University of Pittsburgh School of Medicine, USA


2016 - 2019 

  Postdoctoral Fellow, Department of Molecular Biology

 University of Texas Southwestern Medical Center, USA


2009 - 2015
 Ph.D. in Molecular & Cellular Pharmacology - Dec 2015

 University of Wisconsin-Madison, USA


2005 - 2009

  B.S. with Honors - May 2009
Nanjing University, Nanjing, Jiangsu, China


     

SELECTIVE AWARDS 

2022-2026 NIH/NIA   K01 Mentored Research Scientist Development Award 

2021 UPMC Competitive Medical Research Fund (CMRF) Award

2016-2019 Cancer Research Institute Irvington Postdoctoral Fellowship

2016 Award for Exceptional Contribution to the Phospholipid Signaling Field, FASEB Science Research Conference

2012-2014 Howard Hughes Medical Institute (HHMI) Predoctoral Fellowship


 Jay’s early motivation in seeking a career in science was cultivated at Nanjing University in China where he undertook three years of undergraduate research in biochemistry, cell biology, and pharmacology. In his PhD studies with Dr. Richard A. Anderson, a phospholipid expert at University of Wisconsin-Madison, Jay received extensive research training in cell biology, molecular biology, and biochemistry with a focus on stress-induced membrane trafficking. Supported by Howard Hughes Medical Institute (HHMI) predoctoral fellowship, Jay made a series of discoveries in his PhD work from different lipid effectors in receptor trafficking, lysosomal degradation and autophagy to the non-canonical, kinase-independent role for EGFR (epidermal growth factor receptor) in autophagy initiation. In 2016, Jay started his postdoctoral training as a Cancer Research Institute (CRI) Irvington Postdoctoral Fellow at UT Southwestern working with Dr. James Chen. With further training in advanced biochemistry, Jay quickly uncovered phosphoinositide regulation of the cGAS/STING innate immunity pathway and also contributed to the work on an unconventional role for STING in autophagy induction. His research experience in lysosomal degradation, stress response, autophagy and innate immunity triggered his strong interest in pursuing a science career in aging research. After his postdoc training, in 2019, Jay joined the Aging Institute at the University of Pittsburgh School of Medicine working with Dr. Toren Finkel as a research faculty member. One of his long-term research interests since graduate school has been lysosomes, the dysfunction of which is closely related to aging and age-related pathology. Through a proteomic approach, Jay discovered the PITT (phosphoinositide-initiated membrane tethering and lipid transport) pathway for rapid lysosomal repair with broad implications in aging and age-related diseases. In Jan 2022, he received his NIA K01 career development award. In July 2022, Jay started his independent lab in the Aging Institute and Department of Cell Biology at University of Pittsburgh.  

  • Home
  • Research
  • Publications
  • Team
  • Meet the PI
  • News
  • Resources
  • Join

Copyright © 2022 Jay Tan Lab - University of Pittsburgh - All Rights Reserved.

This website uses cookies.

We use cookies to analyze website traffic and optimize your website experience. By accepting our use of cookies, your data will be aggregated with all other user data.

Accept